Everything about AMH (Anti-Mullerian Hormone)

What is AMH?

AMH stands for Anti-Mullerian Hormone, and is the most reliable predictor of ovarian reserves that we have. It gives an idea of how many eggs are left in the ovaries.

Does AMH tell me how suitable I'll be for egg freezing and IVF?

Yes. AMH is widely used by fertility clinics and specialists as a way to determine how many eggs you’ll be able to retrieve per cycle.

Does AMH say anything about my ability to get pregnant right now?

In short, the answer is No.

We once thought it might do, but more recent data doesn’t show a correlation. A high or low AMH says nothing about your chances of conceiving naturally.

Back in 2011, the medical community thought that we could use AMH as a predictor of your ability to get pregnant right now. Steiner et al (2001) looked at 100 women, of which 18 had ‘low’ AMH levels (under 0.7ng/ml) and if they got pregnant more or less often than the women with ‘normal’ AMH levels. They found that out of the 18 women ‘only’ 7 got pregnant (36%), whereas from the other group 63% got pregnant. That’s promising as a ‘predictor’, but obviously a very small sample size.

Since then, this research has been repeated several times, and doctors now no longer believe that there is a correlation. Steiner et al repeated their research in 2018, this time with about 10 times a bigger sample size. This time they found that there’s no correlation between AMH and ability to get pregnant within 6 or even 12 months. If anything, the women with low AMH conceived more often!

(full research papers here & here)

When should I take my blood test for AMH?

You can take the AMH blood test anytime in your menstrual cycle. If you are on hormonal birth control, you can test AMH and Chlamydia IgG through Grip. You do not have to wait till the third day of your period as neither are impacted by your menstrual cycle.

Overall, AMH levels, using the automated Access AMH assay, appear to be relatively stable across the menstrual cycle. Fluctuations, if any, appear to be small, and therefore, clinicians may advise patients to have AMH levels drawn at any time in the cycle. - Dr. Clarisa R. Gracia, University of Pennsylvania Medicine (full research paper here)

My AMH is lower than average, should I be worry?

If you are on birth control and your AMH is low, we recommend getting off the birth control and retest. You can retest once you have two regular menstrual cycles.

If you are not on birth control and your AMH is low, you may have a higher chance of entering Menopause early. We recommend you to share the lab results with your GP. You can also set up a call with Grip's doctor via hello@gripfertility.com.

We houden je op de hoogte! x Grip



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